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Betaxolol vs timolol. A six-month double-blind comparison.

Author: KimbroughR L, StewartR H, WardR L

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Betaxolol hydrochloride (0.5%) and timolol maleate (0.5%) were compared in a six-month study of 29 patients with glaucoma. Both drugs were effective in lowering intraocular pressure, with betaxolol reducing pressure by 7.6 mm Hg (26%) and timolol reducing pressure by 8.4 mm Hg (29%). Ocular side effects were mild and similar for both treatments.
Paper Details　
Original Abstract of the Article :
Betaxolol hydrochloride (0.5%) and timolol maleate (0.5%) were compared in a six-month randomized, double-blind study involving 29 patients with glaucoma. The two drugs were comparable with regard to efficacy in lowering intraocular pressure. Betaxolol effected an average reduction of 7.6 mm Hg (26%...See full text at original site
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引用元：
https://doi.org/10.1001/archopht.1986.01050130056019

データ提供：米国国立医学図書館（NLM）

Betaxolol vs. Timolol: A Head-to-Head Comparison for Glaucoma

This double-blind study compares the efficacy and safety of betaxolol hydrochloride and timolol maleate, both beta-blocker medications used to lower intraocular pressure in patients with glaucoma. The study found that both drugs were comparable in their ability to lower intraocular pressure. Betaxolol, with its minimal impact on the cardiovascular system, emerges as a viable option for treating glaucoma.

A Tailored Approach to Glaucoma Treatment

This research highlights that, when it comes to glaucoma treatment, there are multiple effective options available. The study's findings provide valuable information for clinicians to choose the best treatment approach based on individual patient factors, including cardiovascular health. This individualized approach can ensure optimal treatment outcomes and patient safety.

Navigating Glaucoma Treatment: A Choice for Patients and Doctors

Glaucoma, like a shifting desert landscape, can present unique challenges for each patient. This study helps illuminate the path forward for those seeking effective treatment. The comparison of betaxolol and timolol provides clinicians with the knowledge to choose the most appropriate treatment for each individual, ensuring a more personalized and effective approach to glaucoma management.

Dr. Camel's Conclusion

Glaucoma, like a vast and unforgiving desert, can pose a significant threat to vision. This study offers valuable insight into the effectiveness of different treatment options, enabling doctors to choose the best path for each patient, like a seasoned traveler selecting the safest route across the dunes.
Date :
  1. Date Completed 1986-02-06
  2. Date Revised 2019-07-04
Further Info :

Pubmed ID

3510612

DOI: Digital Object Identifier

10.1001/archopht.1986.01050130056019

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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