Effects of olanzapine, quetiapine, and risperidone on neurocognitive function in early psychosis: a randomized, double-blind 52-week comparison.

Author: GuHongbin, HamerRobert M, KeefeRichard S E, LiebermanJeffrey A, McEvoyJoseph P, PerkinsDiana O, SweeneyJohn A

Paper Details 
Original Abstract of the Article :
OBJECTIVE: The authors sought to compare the effects of olanzapine, quetiapine, and risperidone on neurocognitive function in patients with early psychosis. METHOD: In a 52-week double-blind, multicenter study, 400 patients early in the course of psychotic illness (<5 years) were randomly assigned ...See full text at original site
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引用元:
https://doi.org/10.1176/ajp.2007.164.7.1061

データ提供:米国国立医学図書館(NLM)

Olanzapine, Quetiapine, and Risperidone: Cognitive Function in Early Psychosis

The world of mental health is constantly seeking new ways to manage psychosis, a serious mental illness. This research compares the effects of three antipsychotic medications, olanzapine, quetiapine, and risperidone, on neurocognitive function in patients with early psychosis. The researchers conducted a long-term, double-blind study to evaluate the impact of these medications on cognitive performance.

Navigating the Labyrinth of Psychosis: Antipsychotic Medications and Cognitive Function

This study found that all three medications, olanzapine, quetiapine, and risperidone, led to significant improvements in neurocognitive function in patients with early psychosis. While the improvements were modest, they were associated with better functional outcomes, suggesting that cognitive enhancement may be a key aspect of managing psychosis.

A Hopeful Glimpse for Early Psychosis

This research offers a glimmer of hope for patients with early psychosis. Antipsychotic medications, specifically olanzapine, quetiapine, and risperidone, may not only manage psychotic symptoms but also improve cognitive function, potentially leading to better overall functioning and quality of life. It's important to remember that every individual responds differently to medication, and close monitoring and individualized treatment plans are essential.

Dr.Camel's Conclusion

Imagine a camel navigating a winding desert path, needing clear vision and sharp senses to avoid obstacles. Similarly, patients with psychosis need cognitive clarity to navigate the challenges of their condition. This research suggests that antipsychotic medications may help to improve cognitive function, allowing these patients to regain their sense of direction and navigate their lives with greater clarity and confidence.

Date :
  1. Date Completed 2007-07-31
  2. Date Revised 2022-03-31
Further Info :

Pubmed ID

17606658

DOI: Digital Object Identifier

10.1176/ajp.2007.164.7.1061

SNS
PICO Info
in preparation
Languages

English

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