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Tapentadol Versus Tramadol: A Narrative and Comparative Review of Their Pharmacological, Efficacy and Safety Profiles in Adult Patients.

Author: DesmeulesJules, PiguetValérie, RollasonVictoria, RouletLucien

Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.

Overview

This narrative review compares the pharmacological, efficacy, and safety profiles of tapentadol and tramadol, two opioid analgesics. Tapentadol is more potent than tramadol but also carries a higher risk of opioid-related adverse effects. The review concludes that tapentadol is not a first-line opioid but may be a suitable alternative for certain patients after careful consideration of their individual circumstances.
Paper Details　
Original Abstract of the Article :
We conducted a narrative review of the literature to compare the pharmacological, efficacy and safety profiles of tapentadol and tramadol, and to assess the clinical interest of tapentadol in adult patients. Tapentadol and tramadol share a mixed mechanism of action, including both mu-agonist and mon...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8318929/

データ提供：米国国立医学図書館（NLM）

Tapentadol vs. Tramadol: A Comparative Review of Pain Medications

Chronic pain is a major public health concern, and opioids are often used to manage pain. This study compares the pharmacological, efficacy, and safety profiles of tapentadol and tramadol, two commonly used opioid analgesics.

Understanding the Nuances of Opioid Treatment

The study provides a comprehensive comparison of tapentadol and tramadol, highlighting their similarities and differences in terms of their mechanisms of action, efficacy, and safety. This research offers valuable information for healthcare providers in making informed decisions about opioid treatment for chronic pain.

Navigating the Complexities of Opioid Therapy

This study emphasizes the importance of careful consideration of the potential risks and benefits of opioid medications. It underscores the need for individualizing treatment plans, considering a patient's specific needs, medical history, and risk factors. This research is a reminder of the complexities of opioid therapy and the need for ongoing monitoring and management to ensure patient safety.

Dr. Camel's Conclusion

This research reminds us that even in the vast desert of pain management, there are many different paths to consider. Tapentadol and tramadol are just two examples of the diverse array of medications available to manage pain, and this study offers valuable insights into their strengths and weaknesses. It's a reminder to always approach pain management with careful consideration and to choose the path that best suits our individual needs.
Date :
  1. Date Completed 2021-12-15
  2. Date Revised 2021-12-15
Further Info :

Pubmed ID

34196947

DOI: Digital Object Identifier

PMC8318929

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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