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Changes in depressive status associated with topical beta-blockers.

Author: DuchC, DuchS, FerrerP, PastóL

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Betaxolol may be less likely than timolol to induce depression in predisposed patients. In a small study of glaucomatous patients, those treated with timolol had higher depression scores than those treated with betaxolol.
Paper Details　
Original Abstract of the Article :
Depression and sexual dysfunction have been related to side effects of topical beta-blockers. We performed a preliminary study in order to determine any difference between a non selective beta-blocker (timolol) and a selective beta-blocker (betaxolol) regarding CNS side effects. Eight glaucomatous p...See full text at original site
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引用元：
https://doi.org/10.1007/BF00917986

データ提供：米国国立医学図書館（NLM）

Navigating the Side Effects of Topical Beta-Blockers: A Study of Depression

The effects of medications, like navigating a desert, can sometimes lead to unexpected encounters, such as changes in mood. This study investigates the potential association between topical beta-blockers, commonly used to treat glaucoma, and depression. The researchers compared the effects of timolol, a non-selective beta-blocker, and betaxolol, a selective beta-blocker, on depressive symptoms in patients with glaucoma. The findings suggest that timolol may be more likely to induce depression in predisposed individuals, prompting further investigation into the potential for selective beta-blockers as an alternative treatment option.

Beta-Blockers and Depression: A Complex Relationship

While beta-blockers are generally safe and effective for treating glaucoma, this study highlights the potential for a complex relationship between these medications and depression. The findings suggest that non-selective beta-blockers, such as timolol, may be more likely to induce depression in susceptible individuals. This information is crucial for healthcare providers to consider when prescribing beta-blockers, ensuring that they are aware of the potential side effects and can tailor treatment plans accordingly.

A Look at Potential Side Effects: Informed Decision-Making

The study emphasizes the importance of informed decision-making when considering treatment options. Patients should have an open and honest conversation with their healthcare providers about potential side effects and discuss alternative treatment options, if necessary. This approach allows patients to actively participate in their healthcare journey, ensuring that they are comfortable with the treatment plan and its potential risks and benefits.

Dr.Camel's Conclusion

The desert of medication side effects can be vast and unpredictable. This study sheds light on the potential association between topical beta-blockers and depression, highlighting the importance of individualized treatment plans and open communication between patients and healthcare providers. By understanding these potential side effects, we can navigate the treatment journey with more awareness and make informed decisions that prioritize patient well-being.

Date :
  1. Date Completed 1992-12-23
  2. Date Revised 2019-10-21
Further Info :

Pubmed ID

1428568

DOI: Digital Object Identifier

10.1007/BF00917986

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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