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Influence of the anti-oestrogens tamoxifen and letrozole on thyroid function in women with early and advanced breast cancer: A systematic review.

Author: AnderssonMichael, Buch-LarsenKristian, GillbergLinn, MarinaDjordje, RasmussenÅse Krogh, SchwarzPeter

Systematic ReviewA review that systematically collects, evaluates, and integrates relevant research to answer a specific research question.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
ReviewAn article that critically examines existing research on a particular topic and summarizes the current state of knowledge in the field.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Tamoxifen and letrozole are anti-oestrogens used to prevent breast cancer recurrence. While their side effects are well-documented, their impact on thyroid function is less clear. This review explores the potential effects of tamoxifen and letrozole on thyroid function and their contribution to weight gain observed in breast cancer patients.
Paper Details　
Original Abstract of the Article :
Breast cancer (BC) is a common type of cancer in women. Advances in therapy options have resulted in higher overall survival rates but side effects of cancer treatment are increasingly in the spotlight. The beneficial effects of anti-oestrogen therapy with tamoxifen and letrozole in the prevention o...See full text at original site
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引用元：
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9883413/

データ提供：米国国立医学図書館（NLM）

Tamoxifen and Letrozole: Navigating the Oasis of Breast Cancer Treatment

Breast cancer, a challenging health concern for many women, is a subject of ongoing research and advancements in treatment. Imagine breast cancer as a vast desert, with treatment options like a series of oases offering relief and hope. This research examines the potential impact of anti-oestrogens, tamoxifen and letrozole, on thyroid function in women with breast cancer, considering the complex interplay between these drugs and overall health.

Tamoxifen and Letrozole: A Complex Interplay with Thyroid Function

The research explores the potential side effects of tamoxifen and letrozole on thyroid function, recognizing the importance of considering this aspect of treatment. It's like studying the unique ecosystem of a desert oasis, understanding how various elements interact and influence each other. The authors acknowledge the potential for weight gain as a side effect of these medications, highlighting the need for further investigation into the underlying mechanisms.

Navigating the Landscape of Breast Cancer Treatment

This research underscores the importance of comprehensive monitoring and patient care in managing breast cancer. It's like a desert traveler, equipped with a thorough understanding of the terrain, ensuring a safe and effective journey. The authors emphasize the need for continued research to fully understand the potential impact of anti-oestrogens on thyroid function and overall health, allowing for more personalized and targeted treatment approaches.

Dr.Camel's Conclusion

This research provides valuable insights into the potential effects of anti-oestrogens on thyroid function in women with breast cancer. Like a wise camel navigating a desert, we must carefully consider the complexities of breast cancer treatment, ensuring a holistic approach that prioritizes both the disease and the patient's overall well-being.

Date :
  1. Date Completed 2023-01-31
  2. Date Revised 2023-02-26
Further Info :

Pubmed ID

35748065

DOI: Digital Object Identifier

PMC9883413

SNS
PICO Info
in preparation
Languages

English

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