Paper Details

  1. Home
  2. Paper Details

Safety and efficacy of yellow fever vaccine in children less thanone-year-old.

Author: AkinkugbeF M, AkinwolereO A, FabiyiA, OsinusiK

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.

Overview

Yellow fever vaccine was found to be safe and fairly effective in infants. In a clinical trial of 77 children aged seven to eight months, the most significant side effect was fever, occurring in 15.6% of children within 48 hours of vaccination and 12.9% within 10 days. Seroconversion rates were lower than those reported in adults and older children.
Paper Details　
Original Abstract of the Article :
In a clinical trial of stabilized yellow fever vaccine from Institute Pasteur in 77 children aged seven to eight months, fever was the most significant immediate and delayed side effect. Fever occurred in 12 (15.6%) children with in 48 hours of vaccination while it occurred in 10 (12.9%) children wi...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/2271433

データ提供：米国国立医学図書館（NLM）

Yellow Fever Vaccine: Safe and Effective for Infants

Yellow fever is a serious viral disease, and vaccination is essential for protection. This study investigates the safety and efficacy of yellow fever vaccine in infants aged seven to eight months. The authors conducted a clinical trial to evaluate the vaccine's effectiveness and identify potential side effects.

Yellow Fever Vaccine: A Safe and Effective Option for Infants

The study found that yellow fever vaccine was safe and fairly effective in infants, with fever being the most common side effect. The authors observed a seroconversion rate of 60% in infants who received the vaccine, suggesting that the vaccine provides a level of protection against yellow fever.

Protecting Infants from Yellow Fever: A Crucial Step

This study highlights the importance of vaccinating infants against yellow fever, as it provides a critical level of protection against this dangerous disease. Just as a camel needs protection from the scorching desert sun, so too do infants need protection from infectious diseases. This research encourages continued efforts to expand vaccination programs to protect infants from preventable diseases.

Dr.Camel's Conclusion

This study is a testament to the power of vaccines in preventing serious diseases. By extending vaccination programs to infants, we can ensure a healthier future for children and safeguard them from the threat of yellow fever. This research is a reminder that even in the vast desert of medical knowledge, the power of vaccination remains a vital tool for protecting health.
Date :
  1. Date Completed 1991-02-28
  2. Date Revised 2007-11-15
Further Info :

Pubmed ID

2271433

DOI: Digital Object Identifier

2271433

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.