Low-dose short-term cyclosporine versus etretinate in psoriasis: improvement of skin, nail, and joint involvement.

Author: FärberL, MahrleG, SchulzeH J, SteiglederG K, WeidingerG

Paper Details 
Original Abstract of the Article :
BACKGROUND: High-dose cyclosporine therapy significantly alleviates psoriasis within 2 to 4 weeks but is associated with a high rate of side effects. Reports are conflicting on the frequency and promptness of relapse after discontinuation of cyclosporine therapy. OBJECTIVE: Our purpose was to compa...See full text at original site
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引用元:
https://doi.org/10.1016/0190-9622(95)90189-2

データ提供:米国国立医学図書館(NLM)

Low-Dose Short-Term Cyclosporine Versus Etretinate in Psoriasis

The quest for effective treatments for [psoriasis] is a journey through a desert of symptoms and side effects. This research explores the efficacy and safety of two medications, [cyclosporine and etretinate], in treating [moderate to severe chronic plaque-type psoriasis]. It's like comparing two different types of oases – one with refreshing water and the other with hidden dangers.

The researchers conducted a [multicenter study] involving [210 patients] randomly assigned to receive either [cyclosporine or etretinate] for [10 weeks]. They found that [low-dose cyclosporine was significantly more effective than etretinate] in reducing [psoriasis area and severity index] and providing relief from [nail involvement and joint complaints]. This is like discovering one oasis with abundant resources and another with limited provisions - the benefits are clear.

The Benefits of Low-Dose Cyclosporine

The study highlights the potential benefits of [low-dose short-term cyclosporine therapy] for [psoriasis], suggesting that it can be a more effective and better-tolerated treatment option than [etretinate]. It's like finding a sweet spot in the desert – a dose that provides relief without causing undue harm.

Navigating Treatment Options for Psoriasis

The research underscores the importance of carefully considering the potential risks and benefits of different treatment options for [psoriasis]. It's crucial to choose a treatment approach that balances effectiveness with safety and tolerability. This is like carefully assessing the quality of water at different oases – ensuring a safe and sustainable source of hydration.

Dr.Camel's Conclusion

This research sheds light on the benefits of [low-dose short-term cyclosporine therapy] for [psoriasis], offering a promising approach for managing this chronic condition. It's like finding a hidden oasis in the desert – a source of relief and hope for patients seeking effective and safe treatments.

Date :
  1. Date Completed 1995-02-16
  2. Date Revised 2019-07-09
Further Info :

Pubmed ID

7822521

DOI: Digital Object Identifier

10.1016/0190-9622(95)90189-2

Related Literature

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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