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Anti-platelet effects of 100 mg alternate day oral aspirin: a randomized, double-blind, placebo-controlled trial of regular and enteric coated formulations in men and women.

Author: BuringJ E, HennekensC H, LipinskaI, RidkerP M, ToflerG H

Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Further research is needed to determine the optimal dose of aspirin to produce a cardiovascular benefit while minimizing side effects, particularly in women.
Paper Details　
Original Abstract of the Article :
While regular use of low-dose aspirin has been recommended for several groups of patients at risk of vascular occlusion, the optimal dose of aspirin to produce a cardiovascular benefit whilst minimizing side effects is uncertain. Further, while enteric coated preparations may reduce gastrointestinal...See full text at original site
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引用元：
https://pubmed.ncbi.nlm.nih.gov/8836865

データ提供：米国国立医学図書館（NLM）

Aspirin's Anti-Platelet Effects: A Closer Look

The use of [aspirin] in preventing [cardiovascular disease] is well-established, but optimizing its dosage remains an ongoing area of research. This study explores the [anti-platelet effects] of [100 mg alternate day oral aspirin] in [men and women], comparing the effects of [regular and enteric coated formulations]. The researchers conducted a [randomized, double-blind, placebo-controlled trial] to determine the optimal dose and formulation of [aspirin] for achieving the desired [anti-platelet effect] while minimizing potential side effects. Their findings provide valuable insights into the efficacy and safety of different [aspirin] regimens.

Navigating the Fine Line: Aspirin Dosage and Safety

This study highlights the importance of carefully considering the [dosage and formulation] of [aspirin] to optimize its [anti-platelet effect] while minimizing potential risks. The researchers found that [100 mg alternate day oral aspirin] can achieve the desired [anti-platelet effect] without significant side effects. This finding underscores the need for personalized approaches to [aspirin] therapy, tailoring the dosage and formulation to meet individual patient needs.

A Balancing Act: Aspirin for Cardiovascular Health

This research provides valuable insights into the use of [aspirin] in [cardiovascular disease] prevention. By carefully considering the [dosage and formulation] of [aspirin], we can potentially maximize its benefits while minimizing potential risks. This study emphasizes the importance of ongoing research in the field of [cardiovascular disease] to develop safe and effective therapies for all patients.

Dr. Camel's Conclusion

Imagine a desert traveler, carefully selecting the right camel for their journey. Just as a traveler must choose the right mount, so too must we choose the right dosage and formulation of [aspirin] to achieve the best possible outcome. This study explores the [anti-platelet effects] of [100 mg alternate day oral aspirin], offering valuable insights for optimizing [aspirin] therapy. By carefully navigating the complex landscape of [aspirin] dosage and formulation, we can work towards improving the cardiovascular health of individuals at risk.

Date :
  1. Date Completed 1996-12-19
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

8836865

DOI: Digital Object Identifier

8836865

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

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