Paper Details

  1. Home
  2. Paper Details

Double-blind crossover comparison of triazolam and lorazepam in the posthypnotic state.

Author: CohnJ B

Randomized Controlled TrialA clinical trial that randomly assigns participants to treatment and control groups to evaluate the effects of an intervention.
Comparative StudyResearch that compares multiple groups/interventions to determine differences/similarities in outcomes/characteristics.
Journal ArticleAn article published in an academic or professional journal that reports original research or scholarly analysis.
Clinical TrialA clinical trial is a planned study conducted on humans to evaluate the efficacy and safety of pharmaceuticals, medical devices, and treatment methods. It aims to explore the possibilities of new treatments and improve the health of patients.
Research Support, Non-U.S. Gov'tResearch funding provided by government agencies outside the United States.

Overview

Triazolam and lorazepam are both effective hypnotics, but lorazepam has more pronounced daytime carryover and side effects.
Paper Details　
Original Abstract of the Article :
A double-blind crossover study compared the hypnotic effect, daytime carryover, and safety of triazolam 0.5 mg, lorazepam 2 mg, and placebo. The two active drugs were similar in hypnotic effect and superior to placebo. Patients reported more drowsiness upon awakening and more sleepiness in mid-morni...See full text at original site
Dr.Camel IconDr.Camel's Paper Summary Blogラクダ博士について

ラクダ博士は、Health Journal が論文の内容を分かりやすく解説するために作成した架空のキャラクターです。
難解な医学論文を、専門知識のない方にも理解しやすいように、噛み砕いて説明することを目指しています。

* ラクダ博士による解説は、あくまで論文の要点をまとめたものであり、原論文の完全な代替となるものではありません。詳細な内容については、必ず原論文をご参照ください。
* ラクダ博士は架空のキャラクターであり、実際の医学研究者や医療従事者とは一切関係がありません。
* 解説の内容は Health Journal が独自に解釈・作成したものであり、原論文の著者または出版社の見解を反映するものではありません。


引用元：
https://pubmed.ncbi.nlm.nih.gov/6142034

データ提供：米国国立医学図書館（NLM）

A Double-Blind Crossover Study: Triazolam vs. Lorazepam

This study, like a thrilling desert adventure, explores the effects of two common sleep medications, triazolam and lorazepam, on sleep patterns and daytime function. The researchers conducted a double-blind crossover study, a rigorous method for comparing treatments, to compare the hypnotic effects, daytime carryover, and safety of both medications. Their findings offer a valuable roadmap for understanding these medications and choosing the best option for individuals struggling with sleep.

Lorazepam's Side Effects: A Cautionary Tale

The study found that both triazolam and lorazepam were more effective than a placebo in promoting sleep. However, lorazepam was associated with a higher incidence of daytime drowsiness and other side effects. This is like navigating a tricky desert path; while both medications offer advantages, lorazepam can have unforeseen consequences that require careful consideration. These findings highlight the importance of choosing the right medication for the individual and considering potential risks and benefits.

Sleep Medications: Navigating the Desert of Insomnia

As we journey through the desert of insomnia, we must be aware of the potential side effects of medications. This study emphasizes that while some sleep medications can be effective, others may come with unwanted consequences. Understanding these side effects, like recognizing the warning signs of a looming sandstorm, can help us make informed decisions about our sleep health.

Dr. Camel's Conclusion

This study provides valuable insights into the world of sleep medications, showcasing the importance of considering both effectiveness and potential side effects. As with any desert expedition, proper preparation and a keen awareness of potential hazards are essential. The findings underscore the need for personalized approaches to sleep treatment, carefully balancing the benefits and risks of medication.
Date :
  1. Date Completed 1984-04-20
  2. Date Revised 2013-11-21
Further Info :

Pubmed ID

6142034

DOI: Digital Object Identifier

6142034

SNS
PICO Info
in preparation
Languages

English

Positive IndicatorAn AI analysis index that serves as a benchmark for how positive the results of the study are. Note that it is a benchmark and requires careful interpretation and consideration of different perspectives.

This site uses cookies. Visit our privacy policy page or click the link in any footer for more information and to change your preferences.